ReguMare helps support the normal hormonal balance of your mare when temperament and marish behaviour adversely affects safe handling, willingness to work and performance. Detach syringe and administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days. Natural or synthetic gestagen therapy may exacerbate existing low-grade or "smoldering" uterine inflammation into a fulminating uterine infection in some instances. The Regumate Dosing Device is easy to dismantle for cleaning and re-lubrication. Each ml of Regu-Mate Solution contains 2.2 mg altrenogest oral progestin. Regumate and Positude are different. Regu-Mate ® (altrenogest) Solution 0.22% may be administered early in the transition period to suppress estrus in mares with inactive ovaries to aid in the management of these mares or to mares later in the transition period with active ovaries to prepare and schedule the mare for breeding. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to the physiological breeding season. Regumate Equine is a hormonal treatment for mares. Regu-Mate Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Talk to your veterinarian about proper use and safe handling of Regu-Mate®. Remove cover from bottle dispensing tip and connect luer lock syringe (without needle). The classic method is daily oral administration of the progestin altrenogest (e.g., Regu-Mate). Pregnant women or women who suspect they are pregnant should not handle Regu-Mate… Suppression of estrus will also facilitate management of prolonged estrus conditions. When treatment is discontinued, mares exhibiting regular estrous cycles return to estrus within 4 to 5 days following treatment and continue to cycle normally. I am not at all a fan of regumate. Replace cover on bottle dispensing tip to prevent leakage. Always wear protective gloves when administering REGU-MATE® (altrenogest) Solution 0.22%. WITHDRAWAL PERIOD. How soon normal oestrus cycles will return post-treatment will again depend on the ovarian activity of the individual mare … Vet is coming tomorrow to look at another horse so I wanted to be able to ask him about different treatment options. Copyright © 2020 Intervet Inc., a subsidiary of Merck & Co., All Rights Reserved. (Note: Do not remove syringe while bottle is inverted as spillage may result.) Regu-Mate ® (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. It’s called Regumate. PRECAUTIONS Various synthetic progestins, including altrenogest, when administered to rats during the embryogenic stage of pregnancy at doses manyfold greater than the recommended equine dose caused fetal anomalies, specifically masculinization of the female genitalia. Helps balance mood and focus for more consistent training and performance. WARNING Regu-Mate® (altrenogest) Solution 0.22% is readily absorbed by the skin. When you stop, she'll probably come into heat within five to 10 days. Mares in winter anestrus with small follicles continued in anestrus and failed to exhibit normal estrus following withdrawal. Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. REGUMATE IN STALLIONS – Effects on Reproductive Performance Patrick M. McCue DVM, PhD, Diplomate American College of Theriogenologists Regumate® or altrenogest is a synthetic progestin approved for suppression of estrus in mares. It is the only such medication proven to have progesterone-type biologic activity in the horse. CONTRAINDICATIONS: Regu-Mate ® (altrenogest) Solution 0.22% is contraindicated for use in mares having a previous or current history of uterine inflammation (i.e., acute, subacute, or chronic endometritis). Draw out appropriate volume of Regu-Mate® solution. Pregnant women or women who suspect they are pregnant should not handle REGU-MATE® (altrenogest) Solution 0.22%. Regu-Mate (altrenogest) Solution 0.22% is indicated to suppress estrus (period of the reproductive cycle when the mare ovulates and, if bred, is likely to conceive) in mares. This product is contraindicated for use in mares with a previous or current history of uterine inflammation. Learn more about REGU-MATE, the original altrenogest solution for horses. We just started my mare on 3 ml of im altrenogest that she gets once a week for four weeks and then possibly reduced down to every three weeks - I THINK this is the p+, but I'm wondering how such a low dose works and how it is different from the p4 ( which I know nothing about) and the boirelease. For complete product information, see accompanying product insert. Possible Side Effects When used as directed on the label, Regu-Mate is usually tolerated well by horses. Would love to hear from someone in the know. Detach syringe and administer solution orally at the rate of 1 mL per 110 pounds body weight (0.044 mg/kg) once daily for 15 consecutive days. Mares have been given Regumate for up to 60 days and then bred with no adverse effect on fertility. Oral altrenogest is no longer under patent, and is … It may be used to suppress and prevent the signs of oestrus in mares, which may be particularly useful early in the breeding season. She had been having intermittent behavior and stiffness issues that after seeing several vets could not be attributed to any lameness issues. 1000ml What is Regu-Mate Solution? Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Direct contact with the skin should be avoided. Regu-Mate Solution Indicated to suppress estrus in mares. This facilitates the attainment of regular cyclicity during the transition from winter anestrus to … It is also commonly used to help maintain pregnancy in mares determined to be at risk of pregnancy loss. Messing withe the body in that manner just isn't something that should be … (Note: Do not remove syringe while bottle is inverted as spillage may result.) Suppression of estrus allows for a predictable occurrence of estrus following drug withdrawal. Excessive use of a syringe may cause the syringe to stick; therefore, replace syringe as necessary. REGU-MATE (altrenogest) Solution 0.22% is indicated to suppress estrus in mares. “Often mare owners/riders are quite happy with their mares’ behavior in late fall, winter, and early spring. Having a previous or current history of uterine inflammation into a fulminating uterine infection in some instances to! … Altren® is manufactured in Minnesota in a matter of hours estrus in mares determined to be able ask. 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